Publications

Olson OC, Quail DF*, and Joyce JA*. (2017) Obesity and the tumor microenvironment. Science 358(6367): 1130-1131. *co-corresponding authors Link to article

Koelwyn GJ*, Quail DF*, Zhang X, and Jones LW. (2017) Exercise-dependent regulation of the tumour microenvironment. Nature Reviews Cancer 17: 620-632.  *co-first authors Link to article

Quail DF*, Olson OC*, Bhardwaj P, Walsh LA, Akkari L, Quick ML, Chen IC, Wendel N, Ben-Chetrit N, Walker J, Holt P, Dannenberg AJ and Joyce JA. (2017) Obesity alters the lung myeloid cell landscape to enhance breast cancer metastasis via IL5 and GM-CSF. Nature Cell Biology 19(8): 974-987. *co-first authors Link to article

Quail DF and Joyce JA. (2017) Microenvironmental landscape of brain tumors. Cancer Cell 31(3): 326-341. Link to article

Quail DF and Joyce JA. (2017) Deciphering mechanisms of resistance to macrophage-targeted therapies. Clinical Cancer Research 23(4): 876-884. Link to article

Olson OC, Kim H, Quail DF, Foley EA and Joyce JA. (2017) Tumor-associated macrophages suppress the cytotoxic activity of antimitotic agents. Cell Reports 19(1): 101-113. Link to article

Quail DF and Joyce JA. (2017) Multifaceted effects of the microenvironment on tumour progression. Nature Reviews Cancer. Link to poster

Quail DF, Bowman RL, Akkari L, Quick ML, Schuhmacher AJ, Huse JT, Holland EC, Sutton JC, and Joyce JA. (2016) The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas. Science 352(6288): aad3018 Link to article

Bowman RL, Klemm F, Akkari L, Pyonteck SM, Sevenich L, Quail DF, Dhara S, Simpson K, Gardner EE, Iacobuzio-Donahue CA, Brennan CW, Tabar V, Gutin PH, and Joyce JA. (2016) Macrophage Ontogeny underlies differences in tumor-specific education in brain malignancies. Cell Reports 17(9): 2445-2459. Link to article

Sevenich L, Bowman RL, Mason SD, Quail DF, Rapaport F, Elie BT, Brogi E, Brastianos PK, Hahn WC, Holsinger LJ, Massague J, Leslie CS, and Joyce JA. (2014) Analysis of tumour- and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S. Nature Cell Biology 16(9): 876-88. Link to article

Quail DF, Zhang G, Hess DA, and Postovit LM. (2014) Nodal promotes invasive phenotypes via a non-canonical Mitogen Activated Protein Kinase-dependent pathway. Oncogene 33(4): 461-473. Link to article

Quail DF and Joyce JA. (2013) Microenvironmental regulation of tumor progression and metastasis. Nature Medicine 19(11): 1423-1437. Link to article

Pyonteck SM*, Akkari L*, Schuhmacher AJ*, Bowman RL, Sevenich L, Quail DF, Olson OC, Quick ML, Huse JT, Teijeiro V, Setty M, Leslie C, Oei Y, Pedraza A, Zhang J, Brennan CW, Sutton JC, Holland EC, Daniel D and Joyce JA. (2013) CSF-1R inhibition alters macrophage polarization and blocks glioma progression. Nature Medicine 19(10): 1264-1272. *co-first authors Link to article

Quail DF, Walsh LA, Zhang G, Findlay S, Fung L, Moreno J, Lewis J, Done S, Hess DA, and Postovit LM. (2012) Embryonic protein Nodal promotes breast cancer vascularization. Cancer Research 72(15): 3851-3863. Link to article

Quail DF, Zhang G, Walsh LA, Broughton H, Hess DA, and Postovit LM. (2012) Embryonic morphogen Nodal promotes breast cancer growth and progression. PLoS One 7(11):e48237. Link to article

Quail DF*, Taylor M*, Walsh LA*, Dieters-Castator D, Das P, Jewer M, Zhang G, and Postovit LM. (2011) Low oxygen levels induce the expression of the embryonic morphogen Nodal. Molecular Biology of the Cell 22(24): 4809-4821. Link to article