Publications

For a full list of publications click here.

McDowell SAC, Luo R, Arabzadeh A, Doré S, Bennett N, Breton V, Karimi E, Rezanejad M, Yang R, Lach K, Issac M, Samborska B, Perus L, Moldoveanu D, Wei Y, Fiset B, Rayes R, Watson I, Kazak L, Guiot MC, Fiset PO, Spicer JD, Dannenberg AJ, Walsh LA* and Quail DF*. (2021) Neutrophil oxidative stress mediates obesity-associated vascular dysfunction and metastatic transmigration. Nature Cancer 2: 545-562. *co-corresponding authors

Koelwyn GJ, Newman AAC, Afonso MS, van Solingen C, Corr EM, Brown EJ, Albers KB, Yamaguchi N, Narke D, Schlegel M, Sharma M, Shanley LC, Barrett TJ, Rahman K, Mezzano V, Fisher EA, Park DS, Newman JD, Quail DF, Nelson ER, Caan BJ, Jones LW, Moore KJ. (2020) Myocardial infarction accelerates breast cancer via innate immune reprogramming. Nature Medicine doi: 10.1038/s41591-020-0964-7

Akkari L, Bowman RL, Tessier J, Klemm F, Handgraaf SM, de Groot M, Quail DF, Tillard L, Gadiot J, Huse JT, Brandsma D, Westerga J, Watts C, Joyce JA. (2020) Dynamic changes in glioma macrophage populations after radiotherapy reveal CSF-1R inhibition as a strategy to overcome resistance. Science Translational Medicine12(552): eaaw7843

Quail DF* and Dannenberg AD*. (2019) The obese adipose tissue microenvironment in cancer development and progression. Nature Reviews Endocrinology 15(3): 139-154. *co-corresponding authors

McDowell SAC and Quail DF (2019) Immunological regulation of vascular inflammation during cancer metastasis. Frontiers Immunology, doi: https://doi.org/10.3389/fimmu.2019.01984

Milette S, Fiset PO, Walsh LA*, Spicer JD* and Quail DF*. (2019) The innate immune architecture of lung tumors and its implication in disease progression. Journal of Pathology 247(5): 589-605. *co-corresponding authors

Olson OC, Quail DF*, and Joyce JA*. (2017) Obesity and the tumor microenvironment. Science 358(6367): 1130-1131. *co-corresponding authors Link to article

Koelwyn GJ*, Quail DF*, Zhang X, and Jones LW. (2017) Exercise-dependent regulation of the tumour microenvironment. Nature Reviews Cancer 17: 620-632.  *co-first authors Link to article

Quail DF*, Olson OC*, Bhardwaj P, Walsh LA, Akkari L, Quick ML, Chen IC, Wendel N, Ben-Chetrit N, Walker J, Holt P, Dannenberg AJ and Joyce JA. (2017) Obesity alters the lung myeloid cell landscape to enhance breast cancer metastasis via IL5 and GM-CSF. Nature Cell Biology 19(8): 974-987. *co-first authors Link to article

Quail DF and Joyce JA. (2017) Microenvironmental landscape of brain tumors. Cancer Cell 31(3): 326-341. Link to article

Quail DF and Joyce JA. (2017) Deciphering mechanisms of resistance to macrophage-targeted therapies. Clinical Cancer Research 23(4): 876-884. Link to article

Olson OC, Kim H, Quail DF, Foley EA and Joyce JA. (2017) Tumor-associated macrophages suppress the cytotoxic activity of antimitotic agents. Cell Reports 19(1): 101-113. Link to article

Quail DF and Joyce JA. (2017) Multifaceted effects of the microenvironment on tumour progression. Nature Reviews Cancer. Link to poster

Quail DF, Bowman RL, Akkari L, Quick ML, Schuhmacher AJ, Huse JT, Holland EC, Sutton JC, and Joyce JA. (2016) The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas. Science 352(6288): aad3018 Link to article

Bowman RL, Klemm F, Akkari L, Pyonteck SM, Sevenich L, Quail DF, Dhara S, Simpson K, Gardner EE, Iacobuzio-Donahue CA, Brennan CW, Tabar V, Gutin PH, and Joyce JA. (2016) Macrophage Ontogeny underlies differences in tumor-specific education in brain malignancies. Cell Reports 17(9): 2445-2459. Link to article

Sevenich L, Bowman RL, Mason SD, Quail DF, Rapaport F, Elie BT, Brogi E, Brastianos PK, Hahn WC, Holsinger LJ, Massague J, Leslie CS, and Joyce JA. (2014) Analysis of tumour- and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S. Nature Cell Biology 16(9): 876-88. Link to article

Quail DF and Joyce JA. (2013) Microenvironmental regulation of tumor progression and metastasis. Nature Medicine 19(11): 1423-1437. Link to article

Pyonteck SM*, Akkari L*, Schuhmacher AJ*, Bowman RL, Sevenich L, Quail DF, Olson OC, Quick ML, Huse JT, Teijeiro V, Setty M, Leslie C, Oei Y, Pedraza A, Zhang J, Brennan CW, Sutton JC, Holland EC, Daniel D and Joyce JA. (2013) CSF-1R inhibition alters macrophage polarization and blocks glioma progression. Nature Medicine 19(10): 1264-1272. *co-first authors Link to article